Trailing 32-14 at intermission, the Trojans opened the second half with a press defense to chip away at the 18-point Tiger lead.
The strategy paid off, as Gaylesville outscored the visitors 18-8 in the third period to draw within 40-32.
The Tigers, though, found a way to offset the Trojan challenge.
Cedar Bluff ran a press-break offense to perfection in the fourth frame, which held Gaylesville to one point the rest of the way.
Rodney Guins led the Tigers with 14 points, while Lucas Pruitt added 12 and Terrell Irons 11.
Tyler Bradford scored 15 points for Gaylesville, followed by Tait Blankenship with 13.
Cedar Bluff began the game with a 7-2 run before the Trojans pulled within 9-8.
The visitors then went on a 12-2 run that gave them a 21-10 first quarter advantage.
Gaylesville managed only four points in the second period, including just two from the field.
At the other end of the court, the Tigers scored 11 points to take an 18-point lead into the half.
CEDAR BLUFF (54): Guins 14, Pruitt 12, Irons 11, Brown 7, Hayes 6, May 2, Nelson 2.
GAYLESVILLE (41): Bradford 15, Blankenship 13, Higgins 8, Mobbs 5